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Deciphering intracellular reaction processes: Bridging Stochastic models with single-cell measurement technologies (II)

Organizer: Elena Sofia D’Ambrosio​ /

17:00 – 17:20 – Information processing by intracellular signaling networks / Presenting author: Andre Levchennko.

17:20 – 17:40 – Scalable inference reveals global transcription regulation from time-resolved single-cell transcriptomics / Presenting author: Dimitris Volteras.

17:40 – 18:00 – Trade-offs between cost and information in cellular prediction / Presenting author: Pieter Rein ten Wolde

18:00 – 18:20 – Real-time inference of intracellular dynamics: A deep learning approach / Presenting author: Elena Sofia D’Ambrosio.

Cell biology

15:00 – 15:20 – Investigating spatial signatures of extrachromosomal DNA in cancer with agent-based modelling / Presenting author: Magnus Haughey

15:20 – 15:40 -Integrated understanding of human PGCLC development using multi-scale mathematical modeling of gene-cel-BMP dynamics/ Presenting author: Michito Ujino

15:40 – 16:00 – Mathematical modeling of subunit formation in Pex14 / Presenting author: Mio Heinrich

16:00 – 16:20 – Identifying the number of rate-limiting steps in transcription initiation, mRNA splicing and nuclear export from mRNA count data / Presenting author: Andrew Nicoll

Deciphering intracellular reaction processes: Bridging Stochastic models with single-cell measurement technologies (I)

Organizers: Elena Sofia & D’Ambrosio​

10:40 – 11:00 – From single cells to microbial consortia and back: Stochastic chemical kinetics coupled to population dynamics / Presenting author: Jakob Ruess.

11:00 – 11:20 – Hawkes process modelling for chemical reaction networks in a random environment / Presenting author: Mark Sinzger D’Angelo

11:20 – 11:40 – A scaling analysis of stochastic models of regulation of protein production in bacterial cells / Presenting author: Philippe Robert

11:40 – 12:00 – Unbiased estimation of second-order parameter sensitivities for stochastic reaction networks / Presenting author: Quentin Badolle

Ecology

15:00 – 15:20 – Assessing the coupled effects of fishing pressure and climate change on West Greenland’s ecosystem using an end-to-end ecosystem model / Presenting author: Matthew Hatton.

15:20 – 15:40 – Critical gap size / Presenting author: Ali Beykzadeh.

15:40 – 16:00 – Speed and shape of population fronts with density dependent diffusion / Presenting author: Beth Stokes.

16:00 – 16:20 – Impact of biodiversity loss on the structure and stability of a marine Antarctic food web / Presenting author: Vanesa Salinas.

Human diseases (II)

17:20 – 17:40 – Modelling immune cell-endometrial cell dynamics in endometriosis / Presenting author: Claire Miller.

17:40 – 18:00 – Stratifying and predicting the progression of acute liver failure during the early phases / Presenting author: Raiki Yoshimura.

18:00 – 18:20 – Mathematical modelling of thyroid hormone dynamics in hypo- and hyperthyroidism / Presenting author: Tony Humphries.

Human diseases (I)

17:20 – 17:40 – Amplitude and frequency variation in stimulated glycemic rhythms / Presenting author: Benoit Huard.

17:40 – 18:00 – Modeling a rare disease: a case in fibrous dysplasia / Presenting author: Juan Carlos Beltrán Vargas.

18:00 – 18:20 – Mathematical modeling of phosphate kinetics for hemodialysis / Presenting author: Morten Andersen.

Mathematical modeling of microbial ecological systems: Bridging theory and experiments (II)

Organizers: Havva Yoldaş​ & Rebeca Gonzalez – Cabaleiro​.

15:00 – 15:20 -Impact of an obligate predator on microbial ecosyste The challenges and benefits of combining modelling and high throughput chemostat arrays / Presenting author: J. Kimberley Summers

15:20 – 15:40 – Harnesing synthetic microbial communities for environmental bioremediation: Insights from genome-scale metabolic modeling / Presenting author: William Scott.

15:40 – 16:00 – Dynamics of encapsulated bacteriophage in the gastrointestinal tract / Presenting author: Carles Barril

16:00 – 16:20 – Closing talk on ‘Mathematical modeling of microbial ecological syste Bridging theory and experiments’ / Presenting author: Havva Yoldas

Applied multi-scale modelling methods in dynamic tissue remodelling

Organizers: Arran B. J. Hodkingson & Anna Zhigun​

15:00 – 15:20 – Towards modelling meniscus tissue regeneration – an interdisciplinary approach / Presenting author: Christina Surulescu.

15:20 – 15:40 – Multiscale modelling and analysis for Glioblastoma Multiforme progression and relapse / Presenting author: Dumitru Trucu.

15:40 – 16:00 – Mathematical modelling of cancer invasion: Phenotypic transitioning provides insight into multifocal foci formation / Presenting author: Zuzanna Szymanska.

16:00 – 16:20 – Hybrid modelling of spatially extended reaction-diffusion processes / Presenting author: Kit Yates.

Genetic and non-genetic routes to phenotypic plasticity in cancer

Organizers: Carmen Ortega – Sabater & Mohit K. Jolly

10:40 – 11:00 – Low dimensionality of phenotypic space as an emergent property of network topology / Presenting author: Pradyumna Vinod Harlapur.

11:00 – 11:20 – 4 states are not equal to 4 dimensions: Proneural-Mesenchymal antagonism dominates the patterns of phenotypic heterogeneity in glioblastoma. / Presenting author: Harshavardhan BV

11:20 – 11:40 – Chromosomal instability as a source of phenotypic variation in childhood B-Acute Lymphoblastic leukemia / Presenting author: Carmen Ortega-Sabater

11:40 – 12:00 – A mathematical model in evolutionary medicine: coordinated inheritance of extrachromosomal DNA types / Presenting author: Elisa Scanu.

Modelling and analysis in cell biology: multi-scale perspectives

Organizers: Martina Conte & Romina Travaglini
10:40 – 11:00 – Modeling non-local cell-cell adhesion: a multi-scale approach / Presenting author: Anna Zhigun.

11:00 – 11:20 – Diffudion-driven instability in bulk-surface reaction-diffusion systems / Presenting author: Davide Cusseddu.

11:20 – 11:40 – A linear optimal control model of immunotherapy for recurrent autoimmune disease / Presenting author: Kamila Azib.

11:40 – 12:00 – A computational multi-scale approach to the therapeutic resistance of protaste cancer / Presenting author: Marianna Cerasuolo.