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Immunology

10:40 – 11:00 – An interpretable prediction method for antibody binding affinity based on mathematical models of structural fluctuations and deep learning/ Presenting author: Barbara Bravi

11:00 – 11:20 – Mathematical dermatology linking eruption morphology and skin disease / Presenting author: Sungrim Seirin-Lee.

11:20 – 11:40 – Hydrodynamic limits for modelling anomalous immune response: a focus on Multiple Sclerosis / Presenting author: Romina Travaglini.

11:40 – 12:00 – Modelling IL-2 signalling dynamics for a single T cell / Presenting author: Siting Miao.

Mathematical insights into telomere length dynamics

Organizers: Marie Doumic & Denis Villemonais
10:40 – 11:00 – Stochastic branching model for the telomeres dynamics including telomerase / Presenting author: Coralie FRITSCH.

11:00 – 11:20 – TBA / Presenting author: Marek KIMMEL.

11:20 – 11:40 – An inverse problem in cell gynamics: estimating the initial distribution of telomere length from the measurements of senescence times / Presenting author: Jules OLAYÉ.

11:40 – 12:00 – Individual cell fate and population dynamics revealed by a mathematical model of replicative senescence / Presenting author: Anaïs RAT.

Multiscale mathematical models in physiological processes and Cancer: from sub-cellular mechanisms to phenotype switching and metastasis (I)

Organizers: Niklas Kolbe & Zuzanna Szymanska.

10:40 – 11:00 – The influence of the geometry and domain size for a reaction-diffusion system with cross-diffusion / Presenting author: Gülsemay Yiğit.

11:00 – 11:20 – Computational investigation of heterogeneous cell phenotypes in the tumour microenvironment / Presenting author: Raluca Eftimie.

11:20 – 11:40 – Cell-state transitions and frequency-dependent interactions among subpopulations together explain the dynamics of spontaneous epithelial-mesenchymal heterogeneity in breast cancer / Presenting author: Paras Jain.

11:40 – 12:00 – Modeling heterogeneous gene expression responses to TGFβ stimulation / Presenting author: Karen Amaral Oliveira

Modelling heterogeneity, adaptation and evolution in cancer

Organizers: LEGRAND Carine & BONNET Céline

10:40 – 11:00 – The statistical physics of gene expression and mRNA expression heterogeneity / Presenting author: James Holehouse.

11:00 – 11:20 – Site frequency spectrum of a rescued population under rare resistant mutations / Presenting author: BONNET Céline.

11:20 – 11:40 – Deterministic modelling of cancer evolutionary dynamics: A phenotype-structured PDE approach / Presenting author: VILLA Chiara.

11:40 – 12:00 – Time-resolved, integrated analysis of clonally evolving genomes / Presenting author: LEGRAND Carine.

Recent advances in modelling cancer invasion

Organizers: Chiara Villa & Alexandre Poulain

10:40 – 11:00 – Proliferation-immuno-evasion trade off: A continuous model for tumor-immune dynamics and therapeutic strategies / Presenting author: Giulia Chiari

11:00 – 11:20 – Multiscale modelling of glioma invasion under the influence of the microenvironment / Presenting author: Martina Conte

11:20 – 11:40 – Travelling waves in heterogeneous cell populations/ Presenting author: Rebecca Crossley

11:40 – 12:00 – Hybrid modelling for cancer invasion and metastasis / Presenting author: Dimitrios Katsaounis

Mathematical models of cancer immunotherapy (I)

Organizers: Juan Belmonte Beitia & Álvaro Martínez Rubio

10:40 – 11:00 – Computational modelling of CAR-T therapy: from pharmacokinetic description to patient-level predictions / Presenting author: Adrià Murias-Closas.

11:00 – 11:20 – Individual patient dynamics of CAR-T cell therapy in lymphoma: Model selection and response prediction / Presenting author: Álvaro Martínez-Rubio.

11:20 – 11:40 – T-cell-cancer cel conjugate dynamics impact time to equilibrium or cancer extinction / Presenting author: Qianci Yang.

11:40 – 12:00 – Modelling tumour escape mechanisms in CAR-T cell treatment of leukemias / Presenting author: Alexis Farman.

Modelling collective cell migration across scales: from individual-based to continuum models

Organizers: Juan Jiménez – Sánchez & Tommaso Lorenzi.

10:40 – 11:00 – Macroscopic limits of kinetic equations for interacting multi-species systems / Presenting author: Gissell Estrada-Rodríguez.

11:00 – 11:20 -Modelling collective migration of phenotypically heterogeneous cell populations: a multiscale kinetic approach/ Presenting author: Nadia Loy.

11:20 – 11:40 – Evolution of phenotypic plasticity leads to tumour heterogeneity with implications for therapy / Presenting author: Simon Syga.

11:40 – 12:00 – Linking discrete and continuous models of cell birth and migration / Presenting author: Duncan Martinson.
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Quantitative approaches to modelling and analysing cancer-immune interactions (I)

Organizers: Eszter Lakatos​ & Barbara Bravi​

10:40 – 11:00 – A hybrid discrete-continuum modelling approach to explore the impact of T-Cell infiltration on anti-tumour immune response / Presenting author: Emma Leschiera

11:00 – 11:20 – Predicting T-cell receptor – peptide-MHC interactions: How can we bridge the two sides of the equations? / Presenting author: David Gfeller.

11:20 – 11:40 – Individual-based modelling of the interaction between cancer and T cells in vitro / Presenting author: Tomás Alarcón

11:40 – 12:00 – Immune evasion impacts the landscape of driver genes during cancer evolution / Presenting author: Luis Zapata Ortiz.

Immunotherapies

10:40 – 11:00 – Agent-based and continuum models for spatial dynamics of infection by oncolytic viruses and its interaction with the immune system / Presenting author: David Morselli.

11:00 – 11:20 – A linear optimal control model of immunotherapy for recurrent autoimmune disease. / Presenting author: Kamilia Azib.

11:20 – 11:40 – Targeting cellular exhaustion as a means to potentially improve immunotherapeutic efforts against solid tumors / Presenting author: Tyler Simmons

11:40 – 12:00 – Optimising cancer vaccine effectiveness via a delay differential equation model of variable T cell avidity / Presenting author: Georgio Hawi

Gaussian processes and inference for dynamical systems

Organizers: John Fricks
10:40 – 11:00 – Gaussian processes for the inference of partially known mechanistic models used for clinical trial / Presenting author: Julien Martinelli.

11:00 – 11:20 – Curve registration for mechanistic models: application for treatment effect analysis / Presenting author: Quentin Clairon.

11:20 – 11:40 – Manifold-constrained Gaussian processes for estimating and assessing differential equation models / Presenting author: Samuel Wong.

11:40 – 12:00 – Parameter stimation for ordinary differential equations with time warping / Presenting author: John Fricks.